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Check if you have access through your login credentials or your institution. 2003 Elsevier Science Ireland Ltd. Ovarian cancer is cancer that begins in the ovaries. How can we help you? What’s New in Ovarian Cancer Research and Treatment? Cancer starts when cells in the body begin to grow out of control. Cells in nearly any part of the body can become cancer, and can spread to other areas of the body.

Ovarian cancer begins in the ovaries. The eggs travel through the fallopian tubes into the uterus where the fertilized egg implants and develops into a fetus. The ovaries are also the main source of the female hormones estrogen and progesterone. One ovary is on each side of the uterus in the pelvis. The ovaries are made up of 3 main kinds of cells. Epithelial tumors start from the cells that cover the outer surface of the ovary. Most ovarian tumors are epithelial cell tumors.

Stromal tumors start from structural tissue cells that hold the ovary together and produce the female hormones estrogen and progesterone. Benign tumors can be treated by removing either the ovary or the part of the ovary that contains the tumor. Most epithelial ovarian tumors are benign, don’t spread, and usually don’t lead to serious illness. There are several types of benign epithelial tumors including serous cystadenomas, mucinous cystadenomas, and Brenner tumors. When looked at under the microscope, some ovarian epithelial tumors don’t clearly appear to be cancerous. LMP tumors tend to affect younger women than the typical ovarian cancers. These tumors grow slowly and are less life-threatening than most ovarian cancers.

LMP tumors can be fatal, but this isn’t common. When someone says that they had ovarian cancer, they usually mean that they had this type of cancer. Undifferentiated epithelial ovarian carcinomas tend to grow and spread more quickly than the other types. The grade classifies the tumor based on how much it looks like normal tissue on a scale of 1, 2, or 3. Grade 3 epithelial ovarian carcinomas look less like normal tissue and usually have a worse outlook.

Grade 2 tumors look and act in between grades 1 and 3. The tumor stage describes how far the tumor has spread from where it started in the ovary. As it becomes more advanced, it may spread to the lung and liver, or, rarely, to the brain, bones, or skin. At surgery, it looks the same as an epithelial ovarian cancer that has spread through the abdomen. Under a microscope, PPC also looks just like epithelial ovarian cancer. PPC seems to develop from cells in the lining of the pelvis and abdomen. These cells are very similar to the cells on the surface of the ovaries.

Some experts believe that PPC may start in the cells lining the fallopian tubes. Like ovarian cancer, PPC tends to spread along the surfaces of the pelvis and abdomen, so it is often difficult to tell exactly where the cancer first started. This type of cancer can occur in women who still have their ovaries, but it is of more concern for women who have had their ovaries removed to prevent ovarian cancer. This cancer does rarely occur in men. Symptoms of PPC are similar to those of ovarian cancer, including abdominal pain or bloating, nausea, vomiting, indigestion, and a change in bowel habits.